Commentary on Genesis
Aphrahat the Persian Sage (270–345)
From the law we heard: "Therefore a man leaves his father and his mother and cleaves to his wife, and they will become one flesh." This is a great and sublime prophecy. Who actually leaves his father and mother when he takes a wife? This is the meaning of the words: man in his original condition loved and worshiped God, his father, and the Holy Spirit, his mother. He did not have any other love. In order to take a wife, man leaves his mother and father, those whom I mentioned above. His mind is thereby diverted by this world. His soul and mind are driven away from God and drawn into this world that he adores and loves "as a man loves the wife of his youth." The love for this wife is different from the love for the father and the mother. Scripture adds, "They will become one flesh." It is true that as some men make one flesh and soul with their wife, and their mind and thoughts are driven away from their father and mother, so those who never take a wife and stay alone may have a single spirit and mind with their father.
Isaac too demonstrated the power of prayer when he prayed over Rebekah, and she gave birth.
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